What Is the Best Over the Counter Medicine for Herpes?

Herpes is so common among Americans. It has two different types, including oral herpes and genital herpes. Oral herpes can be unsightly, itchy and painful. Genital herpes, on the other hand, is considered to be a sexually transmitted disease. While herpes can go away on its own, most of sufferers look for the best over-the-counter medicine. This can help to get rid of herpes fast, with much less pain and prevent recurrent herpes outbreaks. Here are the top 8 best over the counter medicines for herpes.  

  1. ProsurX

ProsurX is one of the best over-the-counter topical medicines for herpes. In particular, it’s used for soothing, healing and preventing oral and genital herpes. Not only can ProsurX help with symptoms, but it can speed up the healing and recovery. The sooner you use ProsurX, the faster you get rid of herpes.


  • Antiviral nanoparticles
  • FDA- approved ingredients (Melissa, Prunella Vulgaris, Tea Tree)
  • Natural skin nourishment (St John’s wort, Aloe Vera, Geranium Maculatum)
  • Vitamin A, C, E
prosurx cream for treating herpes

ProsurX cream


  • Inactivate the HSV that causes herpes
  • Relieve herpes symptoms
  • Stop an outbreak before it starts
  • Reduce the chance of recurrent outbreaks
  • Treatment only takes a couple of days (2-3 days)
  • No negative side effects


  • Only use for external areas of the body
  • Not recommended for children and pregnant women

Read more: ProsurX Reviews

  1. Topical Anesthetics

Topical anesthetics medicines can give relief from symptoms caused by oral herpes. According to the doctors, these medicines can do their jobs, reduce pain effectively. But, they can’t speed up the healing or prevent future outbreaks. Some common topical anesthetics include:

  • Tetracaine (herpes labialis)
  • Lidocaine (genital herpes)
  • Benzocaine (oral herpes)
  • Ophthaine (both oral and genital herpes)

These topical anesthetics can be effective in managing pain. But, they sometimes can cause some negative side effects. For safety, you should follow the directions carefully.

Benzocaine over-the-counter medicine for herpes


  1. Docosanol Cream

This is also one of the best over-the-counter medicines to treat oral herpes. Like prescription medications, this cream can decrease many herpes symptoms, like:

  • Tenderness
  • Itching
  • Tingling

Besides, Docosanol cream can shorten the duration of an outbreak. It’s commonly used to treat genital herpes. So, apply this cream 5 times a day until your herpes outbreak is completely gone. To get the best results, you should apply the cream from the prodrome stage of herpes.

Read more: What Are the Stages of Herpes Outbreaks?

Docosanol cream over-the-counter medicine for herpes

Docosanol cream

  1. Camphor Products

Camphor products are also considered one of the best over-the-counter medicines for herpes. These are pain relievers, so they can offer pain relief from herpes symptoms. Also, they can help with other symptoms, like itching and severe dryness. Blistex is one of the most common camphor products to treat herpes. But, like some over the counter medicines, these products cannot inactivate the HSV.

Camphor Products for herpes

A camphor product


Like ProsurX, HERP-B-GONE uses the power of essential oils to fight against herpes. There are anti-viral, anti-inflammatory and anti-septic properties in the oils. So, they can heal herpes (only oral herpes) very quickly.

Natural ingredients:

  • Peppermint oil
  • Tea tree oil
  • Lemongrass oil
  • Coconut oil


  • Relieve oral herpes symptoms
  • Promote the healing


  • Cause allergic reactions from natural oils

Read more: Herbal Teas Prevent Herpes Outbreaks

Herp B gone

Herp B gone

  1. Abreva Cold sore Cream

Cold sore is a common name of oral herpes. It mostly occurs on the lip around the mouth. Abreva is one type of Docosanol cream. It can help to alleviate cold sore symptoms and speed up the healing time.

Features: FDA-approved treatment


  • Dry clear
  • Moisturize
  • Heal cold sores from inside out


  • Finger application can make cold sores spread

Read more: My Review of Abreva

Abreva for cold sores

Abreva cream

  1. HERP RESCUE Supplement

This supplement is also considered an over-the-counter medicine to treat herpes.


  • L-Lysine
  • Zinc and copper
  • Oregano oil
  • Prunella vulgaris
  • Vitamin C


  • Suppress herpes outbreaks
  • Keep symptoms in check
  • Prevent recurrences
  • Boost immune system


  • Not help immediate relief
Herp rescue supplement for herpes

Herp rescue supplement

  1. Bulletproof+ Supplement

Bulletproof+ is one of the best supplements for herpes and shingles.


  • L-Lysine
  • Vitamin C
  • Zinc


  • Boost the immune system
  • Suppress herpes outbreaks
  • Keep herpes, shingles and blisters at bay
  • Shorten the healing time
  • Prevent herpes recurrences
Bulletproof+ supplement for herpes and shingles

Bulletproof+ supplement

When you recognize herpes symptoms, you should begin your treatment right away. Some over-the-counter medicines can work very well. They help reduce pain and discomfort and speed up the healing time. Some medicines, like ProsurX can even prevent herpes from spreading and coming back. So, consider using these best over-the-counter meds to get rid of herpes fast. If your symptoms persist, ask a doctor for prescription medications.